OpenXR
OpenXR is an open, royalty-free standard for APIs that provide XR applications with access to XR platforms and devices. This is implemented in the XR runtime software supplied by the manufacturer of XR hardware and in the XR software application when it is developed (e.g. via a game engine plugin). Support for OpenXR is potentially useful for preservation purposes β it improves compatability between XR software and XR hardware, allowing modifications to be made, .
OpenXR is developed by a working group managed by the Khronos Group consortium, who describe it as follows:
OpenXR is an API (Application Programming Interface) for XR applications. XR refers to a continuum of real-and-virtual combined environments generated by computers through human-machine interaction and is inclusive of the technologies associated with virtual reality (VR), augmented reality (AR) and mixed reality (MR). OpenXR is the interface between an application and an in-process or out-of-process "XR runtime system", or just "runtime" hereafter. The runtime may handle such functionality as frame composition, peripheral management, and raw tracking information.
Optionally, a runtime may support device layer plugins which allow access to a variety of hardware across a commonly defined interface.
β https://www.khronos.org/registry/OpenXR/specs/1.0/html/xrspec.html
Up until the arrival of OpenXR, support for each manufacturers API would have to be built into the XR applications if they were to be used. OpenXR attempts to solve the problem of compatibility between XR applications and XR hardware. Image source: https://www.khronos.org/openxr/.

Using OpenXR
In order to make use of OpenXR, you need to:
Make use of an XR hardware platform which supports it β see XR Hardware Support below.
Develop XR software which supports it (or add this to the software) β see XR Software Support below.
XR Hardware Support
The Khronos Group report that the following XR runtimes/platforms are compliant with OpenXR:
Acer: Spatial Display Series
ByteDance: Neo3, PICO4 and PICO4 Ultra
Collabora: Monado open-source OpenXR runtime
Magic Leap: Magic Leap 2
Microsoft: Hololens and Mixed Reality Headsets
Qualcomm: Snapdragon Spaces
SteamVR: All supported headsets
Varjo: All Varjo headsets
XR Software Support
The following game engines have native support for OpenXR:
Godot: 4.0+ (built-in); 3.2-3.6 (via plugin)
Unity: 2020.2+ (via plugin)
Unreal Engine 4: 4.27 (via plugin); 4.24-4.26 (via beta plugin)
Unreal Engine 5: 5.0+ (via plugin)
As of Chromium 81, any Chromium-based web browser (e.g. Chrome, Edge) will use OpenXR as its default backend for WebXR content.
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